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St. John's wort is a plant with yellow flowers that has been used for centuries for health purposes, such as for depression and anxiety. This fact sheet answers some frequently asked questions about St. John's wort and depression, and summarizes what the science says about its effectiveness and the research being done.

Conditions

  • Depression

Recommendations

  • None

Interactions & Side Effects

  • Antidepressants. MAO inhibitors, SSRIs, and tricyclics, or possibly the drugs tramadol or sumatripan. Do not take with St. John's wort
  • Stimulants. Ritalin, caffeine, or ephedrine. May interact adversely
  • Statin drugs, theophylline, and any critical medication. St. John's wort may decrease effectiveness
  • The most common side effects of St. John's wort include dry mouth, dizziness, diarrhea, nausea, increased sensitivity to sunlight, and fatigue.

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Disclaimer: This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regime, it is advisible to seek the advice of a licensed healthcare professional.

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