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SAM-e may keep you on your feet physically and emotionally. Researchers found that this amino acid compound can reduce the pain of osteoarthritis as effectively as NSAIDs, while a Harvard study indicates it reduces depression. And in Europe, it's used to treat liver disease.

Conditions

  • Depression
  • Liver disease
  • Pain reliever

Recommendations

  • Up to 1,200 mg, but start low (200 mg daily) and increase the dosage over a few days
  • Take with a B-complex vitamin to avoid a homocysteine buildup

Interactions & Side Effects

  • Antidepressants. Ask your doctor
  • Levodopa for Parkinson's. May reduce side effects, but may also mitigate effectiveness over time

 

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